A description of cattle disease bovine spongiform encephalopathy

BSE is confirmed by either histopathological examination of brain tissue or by the detection of the abnormal form of the prion protein via one of several methods, also requiring brain tissue. Another idea would be to destabilize the structure of PrPSc Prusiner The Economist noted, "Unfortunately, much of the crisis in Europe can be blamed on politicians and bureaucrats.

PrP polymorphism at codonwhere either methionine or valine is encoded, has been described as a key factor influencing human prion susceptibility [31][32][33][34] and seems to be particularly important in vCJD manifestation, as all but one clinical vCJD cases diagnosed so far are homozygous for methionine.

The nature of the transmissible agent is not well understood. One additional form of human prion disease is called kuru. Cases can occur in men and women of all ages, but the average age is 62 years. Since that time, more thancases have been confirmed world-wide.

Nowadays there is strong evidence that also PrPSc conformation plays a critical role, not only in the cross-species transmission events, but also in the existence of different prion strains [24][25][26][27][28][29].

Another disease that affects humans that is similar to BSE is Kuru, which is a neurological disorder that is found in the Fore people of Papua New Guinea contracted. BSE possibly originated as a result of feeding cattle meat-and-bone meal that contained BSE-infected products from a spontaneously occurring case of BSE or scrapie-infected sheep products.

By then, however, infected cattle had already entered the human food supply. Sporadic and familial CJD: Importation of minimal-risk meat products is now allowed from Canada. In the United States, the CDC has refused to impose a national requirement that physicians and hospitals report cases of the disease.

In this figure was challenged in an article in The Review of Veterinary Research which put the figure atStrong evidence collected over the past decade supports the prion theory, but the ability of the BSE agent to form multiple strains is more easily explained by a virus-like agent.

ShareCompartir Cattle such as the one pictured here, which are affected by BSE experience progressive degeneration of the nervous system.

Bovine spongiform encephalopathy

BSE tests are not conducted on cuts of meat, but involve taking samples from the brain of a dead animal to see if the infectious agent is present. After amplifying and then concentrating any PrPSc, the samples are labelled with a fluorescent dye using an antibody for specificity and then finally loaded into a microcapillary tube.

Canada announced two additional cases of BSE from Alberta in early There is strong evidence and general agreement that the outbreak was then amplified and spread throughout the United Kingdom cattle industry by feeding rendered, prion-infected, bovine meat-and-bone meal to young calves.

Risk for Travelers

Managing disease can be a frustrating proposition. Sheep and goats are experimentally susceptible to BSE [7][8][9][10][11] and one confirmed [12] and one suspected [13] BSE-like case have been reported in goats in France and the United Kingdom UKrespectively.

It was found among native peoples of New Guinea who practiced ritualistic cannibalism eating of humans, and their brains, specifically.

As for vCJD in humans, autopsy tests are not always done, so those figures, too, are likely to be too low, but probably by a lesser fraction.

The Basics of Mad Cow Disease

As a result, the full extent of the human vCJD outbreak is still not known. Sincestrong evidence has accumulated for a causal relationship between ongoing outbreaks primarily in Europe of a disease in cattle called bovine spongiform encephalopathy (BSE, or “mad cow disease”) and a disease in humans called variant Creutzfeldt-Jakob disease (vCJD).

A. Bovine spongiform encephalopathy (BSE), sometimes referred to as "mad cow disease", is a chronic degenerative disease affecting the central nervous system of cattle. The disease belongs to the group of transmissible spongiform encephalopathies, which also includes scrapie of sheep and goats and chronic wasting disease (CWD) of elk and deer.

BSE (bovine spongiform encephalopathy) is a progressive neurological disorder of cattle that results from infection by an unusual transmissible agent called a prion.

The nature of the transmissible agent is not well understood. Currently, the most accepted theory is that the agent is a modified form. Description of the disease: Bovine spongiform encephalopathy (BSE) is a fatal neurological disease of adult cattle that was first recognised in Great Britain (GB) and that has been identified in classical (C-type BSE) and atypical forms.

Bovine spongiform encephalopathy

On March 20,the British government announced a possible link between Bovine Spongiform Encephalopathy (BSE), a chronic disease affecting the central nervous system of cattle, and ten cases of a variant form of Creutzfeldt-Jacob Disease (CJD), a related disease among humans.

BSE (bovine spongiform encephalopathy) is a progressive neurological disorder of cattle; its symptoms are similar to a disease of sheep, called scrapie.

BSE has been called "mad cow disease." BSE.

A description of cattle disease bovine spongiform encephalopathy
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Bovine Spongiform Encephalopathy (BSE) - The Cattle Site